Translational bioinformatics: linking knowledge across biological and clinical realms.

TitleTranslational bioinformatics: linking knowledge across biological and clinical realms.
Publication TypeJournal Article
Year of Publication2011
AuthorsSarkar, IN, Butte, AJ, Lussier, YA, Tarczy-Hornoch, P, Ohno-Machado, L
JournalJ Am Med Inform Assoc
Volume18
Issue4
Pagination354-7
Date Published2011 Jul-Aug
ISSN1527-974X
iDASH CategoryGenomics
AbstractNearly a decade since the completion of the first draft of the human genome, the biomedical community is positioned to usher in a new era of scientific inquiry that links fundamental biological insights with clinical knowledge. Accordingly, holistic approaches are needed to develop and assess hypotheses that incorporate genotypic, phenotypic, and environmental knowledge. This perspective presents translational bioinformatics as a discipline that builds on the successes of bioinformatics and health informatics for the study of complex diseases. The early successes of translational bioinformatics are indicative of the potential to achieve the promise of the Human Genome Project for gaining deeper insights to the genetic underpinnings of disease and progress toward the development of a new generation of therapies.
DOI10.1136/amiajnl-2011-000245
Alternate JournalJ Am Med Inform Assoc
PubMed ID21561873

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