CYCORE: Cyberinfrastructure for Cancer Comparative Effectiveness Research

We propose to create a highly customizable suite of sensors capable of supporting cancer comparative effectiveness research (CER)  in a variety of patients, settings, and clinical trials based on research that we begin in 2010 with the development of an initial highly successful prototype of CYCORE (CYberinfrastructure for Comparative effectiveness Research). CYCORE is innovative because systems that facilitate greater patient engagement with clinicians and researchers, such as those that enable remote and even real-time monitoring of patients' symptoms and other health-related outcomes have almost all been developed and tested in patients with chronic diseases such as diabetes, asthma, heart failure, chronic obstructive pulmonary disease and chronic wound management. We propose to enhance CYCORE by: 1) improving scalability and performance; 2) expanding capability for new sensors and addressing fault tolerance and self-healing; 3) introducing a new cancer control use case for CYCORE; 4) incorporating new algorithms that support the detection and analysis of outcomes important in cancer CER; 5) improving security, privacy and data sharing capabilities of CYCORE; 6) developing and implementing a model for sustainability; and 7) expanding and enriching the community of CYCORE users.

Cyberinfrastructure for Cancer Comparative Effectiveness Research is funded by the National Cancer Institute, part of the National Institutes of Health. (R01CA177996)

Principal Investigators

Kevin PatrickKevin Patrick, MD, MS, is a Professor of Family and Preventive Medicine in the UCSD School of Medicine and Director of the Center for Wireless and Population Health Systems at UCSD's Qualcomm Institute/Calit2.  His research focuses on the use of information and communication technology to measure and improve health-related behaviors of individuals and populations. He is Director of the Robert Wood Johnson Foundation (RWJF) Health Data Exploration Project and a Senior Advisor to the RWJF Active Living Research program.



Susan Peterson

Susan K. Peterson, PhD, MPH, is Associate Professor of Behavioral Science at the University of Texas, MD Anderson Cancer Center (MDACC).  Dr. Peterson’s research focuses on psychosocial and behavioral outcomes of genetic testing for hereditary cancer syndromes in cancer survivors and their families, as well as the integration of genetic services into general oncology care. Dr. Peterson's ongoing and completed research has focused on cancer survivors' and families' decision-making about genetic testing and receiving genetic test results, and the subsequent psychological and behavioral impact of those decisions.  Her research encompasses several hereditary cancer syndromes, including hereditary colorectal cancers, hereditary breast and ovarian cancers, and Li-Fraumeni syndrome.  Dr. Peterson also has a major research interest in the development and evaluation of novel, e-Health interventions for pediatric and adult cancer survivors, persons at risk for hereditary cancers, and health care providers. A cross-cutting theme across many of her studies is the integration of technological advances for measurement and monitoring of behavioral outcomes, communication and education, decision-making and psycho-oncology.