Fri Dec 16, 2011
Jane C Burns
Professor, Division of Allergy and Immunology, UCSD
Kawasaki Disease (DBP 1)
Dr. Burns will be giving a talk about her recent article "Association of Kawasaki disease with tropospheric wind patterns." The causal agent of Kawasaki disease (KD) remains unknown after more than 40 years of intensive research. The number of cases continues to rise in many parts of the world and KD is the most common cause of acquired heart disease in childhood in developed countries. Analyses of the three major KD epidemics in Japan, major non-epidemic interannual fluctuations of KD cases in Japan and San Diego, and the seasonal variation of KD in Japan, Hawaii, and San Diego, reveals a consistent pattern wherein KD cases are often linked to large-scale wind currents originating in central Asia and traversing the north Pacific. Results suggest that the environmental trigger for KD could be wind-borne. Efforts to isolate the causative agent of KD should focus on the microbiology of aerosols
Dr. Jane C. Burns is a native of San Francisco, California. She received her M.D. degree at the University of North Carolina in Chapel Hill in 1978 and completed her pediatric residency and Chief Residency at the University of ColoradoSchool of Medicine in Denver, Colorado. In 1983, Dr. Burns moved to Harvard Medical School and the Boston Children’s Hospital for additional training in pediatric infectious diseases and molecular virology. She joined the faculty at Harvard in 1986 and in 1990 moved to San Diego, California, where she joined the faculty at the University of California as an Assistant Professor. Dr. Burns moved up through the ranks and was appointedProfessor of Pediatrics in 1999. She was appointed Chief of the Division ofAllergy, Immunology, and Rheumatology in 2000. Currently, Dr. Burns is Director of the Kawasaki Disease Research Center at UCSD/Rady Children’s Hospital where she leads a multidisciplinary team that cares for 80-90 new Kawasaki disease patients each year and follows over 1,200 families in the KD Clinic. Her passion for studies of Kawasaki disease has spanned almost three decades with her first publication on KD in 1982. In addition to her academic pursuits, Dr. Burns is the mother of two daughters. Her husband, John B. Gordon M.D., is an interventional cardiologist who cares for adults with long-term sequelae of KD. Together, Burns and Gordon with a team from UCSD have launched The Adult KDCollaborative, a long-range epidemiologic and clinical study of cardiovascular biomarkers and functional studies in adults who suffered from KD in childhood.
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